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Arbor Vita's research programs focus on diseases
linked to the role of PDZ proteins in cell signaling pathways. Arbor
Vita has selected four key therapeutic areas for internal drug development:
oncology, neurology, virology and inflammation/autoimmunity. These were
selected based on several criteria:
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- The
PDZ protein or PL plays a significant role in the disease
- Open
intellectual property environment (i.e., areas that have not
been widely protected by existing patents allowing Arbor Vita
to adequately protect its discoveries)
- Clear
clinical indication with significant unmet medical need
- Ability to develop treatments with superior efficacy and side
effect profiles in systems that are amenable to rapid clinical
development.
Three product development programs are nearing
clinical trials: NA-1 for treatment
of stroke, AVC Dx-1 for diagnosis
of cervical cancer and AVC Dx-2
for testing for avian influenza.
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