Feasibility Study of a Human Papillomavirus E6 Oncoprotein Test for Diagnosis of Cervical Precancer and Cancer

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Johannes Schweizer1*, Peter S. Lu1, Charles W. Mahoney1, Marthe Berard-Bergery1, Minh Ho1, Valli Ramasamy1, Jon E. Silver1, Arnima Bisht1, Yassine Labiad1, Roger B. Peck2, Jeanette Lim2, Jose Jeronimo2, Roslyn Howard3,Patti E. Gravitt3,4 and Philip E. Castle5

Arbor Vita Corporation, Fremont, California1; Program for Appropriate Technology in Health, Seattle, Washington2 ; Departments of Epidemiology3 and of Molecular Microbiology and Immunology,4 Johns Hopkins University, Baltimore, Maryland; and Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, Maryland5

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